Pepperoni Pizza Grilled Cheese

What could be better than the combination of grilled cheese and pizza? This pepperoni pizza grilled cheese sandwich recipe is the perfect mix of two classic favorites! Full of flavor and super easy to make!

A pizza grilled cheese sandwich cut in half stacked on a white plate.

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Melted cheese, buttery garlic bread toast, spicy pepperoni... what more could you ask for? This tasty sandwich is the combination of two of the ultimate comfort foods and is loaded with gooey cheese and a ton of pizza flavor! These pizza grilled cheese sandwiches make an easy weeknight dinner, a quick lunch or a super tasty after school snack!

A white plate with a pepperoni pizza grilled cheese sandwich cut in half and stacked on it. It is sitting on a black and white checked linen.

Here is why this recipe is amazing:

Everyone loves it! - This is a family favorite that everyone loves! You get all of the deliciousness of pizza without having to order out!
You can personalize it- One of our favorite things about these sandwiches is that everyone can personalize them to their tastes! You can make them with just pepperoni and cheese or add any of your favorite pizza toppings! Some of the ones we love are green peppers, black olives, mushrooms, and bacon! The whole family can make their own variation of pizza sandwich!

Ingredients needed:

Here is a visual overview of the ingredients in the recipe. Scroll down to the recipe at the bottom for quantities.

The ingredients for pepperoni pizza grilled cheese on a marble countertop. Provolone cheese slices, deli pepperoni slices and mozzarella slices are on a wooden chopping block. There is also butter, Italian bread, garlic powder, Italian seasoning and marinara sauce.

8 Slices Italian Bread
8 tablespoon Butter- softened to room temperature
½ teaspoon Italian seasoning
½ teaspoon Garlic Powder
Pepperoni- 16 slices deli size or 48 slices of regular pepperoni
8 Slices Provolone Cheese
8 Slices Mozzarella Cheese
8 tablespoon Pizza Sauce or Marinara Sauce

How to make Pizza Grilled Cheese Sandwiches

Place softened butter in a small bowl add garlic powder and Italian seasoning, stir together until everything is well mixed.

A white bowl with a butter and herb mixture in it.

Butter one side of each slice of bread with the butter and herb mixture.

A slice of bread spread with garlic and herb butter.

Place bread with the buttered side down in a large nonstick skillet over medium low heat.

Place one slice of mozzarella and one slice of provolone on the piece of bread.

A piece of bread with two slices of white cheese on it.

Then spoon about 2 tablespoons of pizza sauce onto the slices of cheese and spread evenly.

A piece of bread with two slices of cheese on top with marinara sauce spread in the center.

Layer 4 slices of pepperoni onto the pizza sauce. If using regular size pepperoni place 6 pieces on the cheese layer.

A piece of bread with cheese and pepperoni layered on top.

Place another slice of mozzarella an provolone over the pepperoni layer.

A piece of bread with cheese and pepperoni layered on it.

Top off the sandwich with another piece of bread, butter side up.

A piece of bread with garlic herb butter spread on it on top of a sandwich in a cast iron pan.

Allow the sandwich to cook for 3-4 minutes over medium heat and then carefully flip and continue cooking an additional 3-4 minutes.

Continue cooking, flipping occasionally until the sandwich is golden brown with a crispy exterior and the cheese melts.

A close up of a pepperoni and cheese grilled sandwich.

Frequently asked questions, answers and tips:

Use your favorite sauce

Whether you love a specific jar of pasta or pizza sauce or have a special recipe for homemade marinara sauce use whatever you love! If you prefer garlic butter or alfredo sauce on your pizza you can use that too!

Use your favorite bread

We like to use Italian or white bread for these sandwiches because those kinds of bread take on the flavor of the garlic, Italian herbs and butter really well. However if you prefer another type of bread you can use it! Sourdough is a great option, wheat bread, or even Texas toast!

What to serve with these sandwiches?

For a quick meal serve these up with a side salad, or some tomato soup! For a delicious lunch pair them with some chopped fruits or veggies like a sliced apple or carrot sticks.

Pepperoni Pizza Grilled Cheese

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Prep Time 5

Cook Time 10

Course Main Course

Cuisine American

Servings

Calories

Equipment

1 Small Bowl
1 Nonstick Skillet

Ingredients

8 Slices Italian Bread
8 tablespoon Butter softened
½ teaspoon Italian Seasoning
½ teaspoon Garlic Powder
16 Slices Pepperoni- Deli size
8 Slices Provolone Cheese
8 Slices Mozzarella Cheese
8 tablespoon Marinara or Pizza Sauce

Disclosure

Nutritional facts are estimates and are provided as a courtesy to the reader. Please utilize your own brand nutritional values to double check against our estimates. Nutritional values are calculated via a third party. Changing ingredients, amounts or cooking technique will alter the estimated nutritional calculations.